25-Hydroxyvitamin D(3) is a natural chemopreventive agent against carcinogen induced precancerous lesions in mouse mammary gland organ culture

Despite the role of vitamin D(3) endocrine system in prevention of mammary gland transformation in animal models, use of 1,25(OH)(2)D(3) in clinical settings is precluded due to its toxicity in vivo. Therefore much effort has been placed in developing relatively non-toxic vitamin D analogs. Recently...

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Bibliographic Details
Main Authors: Peng, Xinjian, Hawthorne, Michael, Vaishnav, Avani, St-Arnaud, René, Mehta, Rajendra G.
Format: Artigo
Language:Inglês
Published: 2008
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Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2695979/
https://ncbi.nlm.nih.gov/pubmed/18205042
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s10549-008-9900-0
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