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Use of a combined cryo-EM and X-ray crystallography approach to reveal molecular details of bacterial pilus assembly by the chaperone/usher pathway

Many bacteria assemble hair-like fibers termed pili or fimbriae on their cell surface. These fibers mediate adhesion to various surfaces, including host cells, and play critical roles in pathogenesis. Pili are polymers composed of thousands of individual subunit proteins. Understanding how these sub...

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Detalhes bibliográficos
Main Authors: Li, Huilin, Thanassi, David G.
Formato: Artigo
Idioma:Inglês
Publicado em: 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2695944/
https://ncbi.nlm.nih.gov/pubmed/19356973
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.mib.2009.03.002
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