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Down-Regulation of a Manganese Transporter in the Face of Metal Toxicity

The yeast Smf1p Nramp manganese transporter is posttranslationally regulated by environmental manganese. Smf1p is stabilized at the cell surface with manganese starvation, but is largely degraded in the vacuole with physiological manganese through a mechanism involving the Rsp5p adaptor complex Bsd2...

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Auteurs principaux: Jensen, Laran T., Carroll, Mark C., Hall, Matthew D., Harvey, Christopher J., Beese, Sara E., Culotta, Valeria C.
Format: Artigo
Langue:Inglês
Publié: The American Society for Cell Biology 2009
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC2695789/
https://ncbi.nlm.nih.gov/pubmed/19369420
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1091/mbc.E08-10-1084
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