A multicenter phase II study of the combination of oxaliplatin, irinotecan and capecitabine in the first-line treatment of metastatic colorectal cancer

The triple drug combination consisting of irinotecan, oxaliplatin and 5-fluorouracil (FOLFOXIRI) has demonstrated higher activity and efficacy compared to the doublet FOLFIRI. 5-Fluorouracil could be substituted in FOLFOXIRI regimen by capecitabine, an oral fluoropyrimidine with similar efficacy. Re...

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Detalhes bibliográficos
Main Authors: Vasile, E, Masi, G, Fornaro, L, Cupini, S, Loupakis, F, Bursi, S, Petrini, I, Di Donato, S, Brunetti, I M, Ricci, S, Antonuzzo, A, Chiara, S, Amoroso, D, Andreuccetti, M, Falcone, A
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2009
Assuntos:
Clinical Study
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2695688/
https://ncbi.nlm.nih.gov/pubmed/19436300
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjc.6605075
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