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A Cell-penetrating Helical Peptide as a Potential HIV-1 Inhibitor

The capsid domain of the human immunodeficiency virus type 1 (HIV-1) Gag polyprotein is a critical determinant of virus assembly, and is therefore a potential target for developing drugs for AIDS therapy. Recently, a 12-mer α-helical peptide (CAI) was reported to disrupt immature- and mature-like ca...

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Bibliografiske detaljer
Main Authors: Zhang, Hongtao, Zhao, Qian, Bhattacharya, Shibani, Waheed, Abdul A., Tong, Xiaohe, Hong, Anita, Heck, Susanne, Curreli, Francesca, Goger, Michael, Cowburn, David, Freed, Eric O., Debnath, Asim K.
Format: Artigo
Sprog:Inglês
Udgivet: 2008
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2695608/
https://ncbi.nlm.nih.gov/pubmed/18374356
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jmb.2008.02.066
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