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A Cell-penetrating Helical Peptide as a Potential HIV-1 Inhibitor
The capsid domain of the human immunodeficiency virus type 1 (HIV-1) Gag polyprotein is a critical determinant of virus assembly, and is therefore a potential target for developing drugs for AIDS therapy. Recently, a 12-mer α-helical peptide (CAI) was reported to disrupt immature- and mature-like ca...
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| Main Authors: | , , , , , , , , , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
2008
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2695608/ https://ncbi.nlm.nih.gov/pubmed/18374356 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jmb.2008.02.066 |
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