Antagonism by haloperidol and its metabolites of mechanical hypersensitivity induced by intraplantar capsaicin in mice: role of sigma-1 receptors

RATIONALE: We evaluated the effects of haloperidol and its metabolites on capsaicin-induced mechanical hypersensitivity (allodynia) and on nociceptive pain induced by punctate mechanical stimuli in mice. RESULTS: Subcutaneous administration of haloperidol or its metabolites I or II (reduced haloperi...

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Autors principals: Entrena, José M., Cobos, Enrique J., Nieto, Francisco R., Cendán, Cruz M., Baeyens, José M., Del Pozo, Esperanza
Format: Artigo
Idioma:Inglês
Publicat: Springer-Verlag 2009
Matèries:
Original Investigation
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2695546/
https://ncbi.nlm.nih.gov/pubmed/19326101
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00213-009-1513-8
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