Simvastatin Decreases Lipopolysaccharide-induced Pulmonary Inflammation in Healthy Volunteers

Rationale: Simvastatin inhibits inflammatory responses in vitro and in murine models of lung inflammation in vivo. As simvastatin modulates a number of the underlying processes described in acute lung injury (ALI), it may be a potential therapeutic option. Objectives: To investigate in vivo if simva...

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Detalhes bibliográficos
Main Authors: Shyamsundar, Murali, McKeown, Scott T. W., O'Kane, Cecilia M., Craig, Thelma R., Brown, Vanessa, Thickett, David R., Matthay, Michael A., Taggart, Clifford C., Backman, Janne T., Elborn, J. Stuart, McAuley, Daniel F.
Formato: Artigo
Idioma:Inglês
Publicado em: American Thoracic Society 2009
Assuntos:
B. Critical Care
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2695496/
https://ncbi.nlm.nih.gov/pubmed/19324974
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1164/rccm.200810-1584OC
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