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Vaccine Adjuvants Alter TCR-Based Selection Thresholds
How TCR specificity evolves in vivo following protein vaccination is central to the development of T helper cell function. Most models of clonal selection in the T helper cell compartment favor TCR affinity-based thresholds. Here, we demonstrate that depot-forming vaccine adjuvants do not require TL...
Αποθηκεύτηκε σε:
| Κύριοι συγγραφείς: | , , , , |
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| Μορφή: | Artigo |
| Γλώσσα: | Inglês |
| Έκδοση: |
2008
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| Θέματα: | |
| Διαθέσιμο Online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2695494/ https://ncbi.nlm.nih.gov/pubmed/18450485 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.immuni.2008.03.014 |
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