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Erbin regulates NRG1 signaling and myelination

Neuregulin 1 (NRG1) plays a critical role in myelination. However, little is known about regulatory mechanisms of NRG1 signaling. We show here that Erbin, a protein that contains leucine-rich repeats (LRR) and a PSD95-Dlg-Zol (PDZ) domain and that interacts specifically with ErbB2, is necessary for...

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Bibliografske podrobnosti
Main Authors: Tao, Yanmei, Dai, Penggao, Liu, Yu, Marchetto, Sylvie, Xiong, Wen-Cheng, Borg, Jean-Paul, Mei, Lin
Format: Artigo
Jezik:Inglês
Izdano: National Academy of Sciences 2009
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC2695084/
https://ncbi.nlm.nih.gov/pubmed/19458253
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0901844106
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