Curcumin Circumvents Chemoresistance in vitro and Potentiates the Effect of Thalidomide and Bortezomib against Human Multiple Myeloma in Nude Mice Model

Curcumin (diferuloylmethane), a yellow pigment in turmeric, has been shown to inhibit the activation of NF-κB, a transcription factor closely linked to chemoresistance in multiple myeloma (MM) cells. Whether curcumin can overcome chemoresistance and enhance the activity of thalidomide and bortezomib...

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Detalhes bibliográficos
Main Authors: Sung, Bokyung, Kunnumakkara, Ajaikumar B., Sethi, Gautam, Anand, Preetha, Guha, Sushovan, Aggarwal, Bharat B.
Formato: Artigo
Idioma:Inglês
Publicado em: 2009
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2694943/
https://ncbi.nlm.nih.gov/pubmed/19372569
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1535-7163.MCT-08-0905
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