Mitogen-activated protein kinase pathway mediates N-(4-hydroxyphenyl)-retinamide-induced neuronal differentiation in the ARPE-19 human retinal pigment epithelial cell line

We have shown previously that N-(4-hydroxyphenyl)retinamide (4HPR, fenretinide), a retinoic acid derivative, induces neuronal differentiation in cultured human retinal pigment epithelial (RPE) cells (Chen et al., 2003, J Neurochem 84:972–981). We asked the question whether the mitogen-activated prot...

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Hauptverfasser: Samuel, William, Kutty, R. Krishnan, Sekhar, Sonia, Vijayasarathy, Camasamudram, Wiggert, Barbara, Redmond, T. Michael
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2008
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2694741/
https://ncbi.nlm.nih.gov/pubmed/18410500
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1471-4159.2008.05409.x
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