Functional diversity for REST (NRSF) is defined by in vivo binding affinity hierarchies at the DNA sequence level

The molecular events that contribute to, and result from, the in vivo binding of transcription factors to their cognate DNA sequence motifs in mammalian genomes are poorly understood. We demonstrate that variations within the DNA sequence motifs that bind the transcriptional repressor REST (NRSF) en...

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Main Authors: Bruce, Alexander W., López-Contreras, Andrés J., Flicek, Paul, Down, Thomas A., Dhami, Pawandeep, Dillon, Shane C., Koch, Christoph M., Langford, Cordelia F., Dunham, Ian, Andrews, Robert M., Vetrie, David
格式: Artigo
語言:Inglês
出版: Cold Spring Harbor Laboratory Press 2009
主題:
Letter
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC2694481/
https://ncbi.nlm.nih.gov/pubmed/19401398
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gr.089086.108
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