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Effect of chronic morphine on the dentate gyrus neurogenic microenvironment

Opiates, such as morphine, decrease neurogenesis in the postnatal hippocampal subgranular zone (SGZ) by inhibiting progenitor proliferation and maturation. However, it is not known how morphine influences the growth factors and vasculature that encompass the neurogenic SGZ microenvironment. We exami...

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Bibliographic Details
Main Authors: Arguello, Amy A., Fischer, Stephanie J., Schonborn, Joshua R., Markus, Richard W., Brekken, Rolf A., Eisch, Amelia J.
Format: Artigo
Language:Inglês
Published: 2009
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2694451/
https://ncbi.nlm.nih.gov/pubmed/19356684
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neuroscience.2009.01.020
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