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A quantitative, high-throughput screen for protein stability

In proteomic research, it is often necessary to screen a large number of polypeptides for the presence of stable structure. Described here is a technique (referred to as SUPREX, stability of unpurified proteins from rates of H/D exchange) for measuring the stability of proteins in a rapid, high-thro...

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Detalhes bibliográficos
Main Authors: Ghaemmaghami, S., Fitzgerald, M. C., Oas, T. G.
Formato: Artigo
Idioma:Inglês
Publicado em: The National Academy of Sciences 2000
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC26941/
https://ncbi.nlm.nih.gov/pubmed/10890887
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