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NSOM/QD-Based Direct Visualization of CD3-Induced and CD28-Enhanced Nanospatial Coclustering of TCR and Coreceptor in Nanodomains in T Cell Activation

Direct molecular imaging of nano-spatial relationship between T cell receptor (TCR)/CD3 and CD4 or CD8 co-receptor before and after activation of a primary T cell has not been reported. We have recently innovated application of near-field scanning optical microscopy (NSOM) and immune-labeling quantu...

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Détails bibliographiques
Auteurs principaux: Zhong, Liyun, Zeng, Gucheng, Lu, Xiaoxu, Wang, Richard C., Gong, Guangming, Yan, Lin, Huang, Dan, Chen, Zheng W.
Format: Artigo
Langue:Inglês
Publié: Public Library of Science 2009
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC2693923/
https://ncbi.nlm.nih.gov/pubmed/19536289
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0005945
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