15-Deoxy-Δ(12,14)-ProstaglandinJ2 Regulates Dedifferentiation through Peroxisome Proliferator-Activated Receptor-γ-Dependent Pathway but Not COX-2 Expression in Articular Chondrocytes

Peroxisome proliferator-activated receptors-γ (PPAR-γ) is critical for phenotype determination at early differentiation stages of mesenchymal cells, whereas its physiological role is unclear. Therefore, we investigated the role of 15-deoxy-Δ(12,14)-prostaglandinJ2 (15d-PGJ2), the natural receptor li...

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Detalhes bibliográficos
Main Authors: Lee, Ji-Hye, Yu, Seon-Mi, Yoon, Eun-Kyung, Lee, Won-Kil, Jung, Jae-Chang, Kim, Song-Ja
Formato: Artigo
Idioma:Inglês
Publicado em: The Korean Academy of Medical Sciences 2007
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Original Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2693859/
https://ncbi.nlm.nih.gov/pubmed/17982241
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3346/jkms.2007.22.5.891
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