Increased basolateral sorting of carcinoembryonic antigen in a polarized colon carcinoma cell line after cholesterol depletion-Implications for treatment of inflammatory bowel disease

AIM: To investigate a possible increase of basolateral expression of carcinoembryonic antigen (CEA) by interfering with the apical transport machinery, we studied the effect of cholesterol depletion on CEA sorting and secretion. METHODS: Cholesterol depletion was performed in polarized Caco-2 cells...

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Detalhes bibliográficos
Main Authors: Ehehalt, Robert, Krautter, Markus, Zorn, Martin, Sparla, Richard, Füllekrug, Joachim, Kulaksiz, Hasan, Stremmel, Wolfgang
Formato: Artigo
Idioma:Inglês
Publicado em: The WJG Press and Baishideng 2008
Assuntos:
Rapid Communication
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2693746/
https://ncbi.nlm.nih.gov/pubmed/18330942
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3748/wjg.14.1528
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