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COOH-terminal deletion of HBx gene is a frequent event in HBV-associated hepatocellular carcinoma

AIM: To investigate the hepatitis B virus (HBV) x gene (HBx) state in the tissues of HBV-related hepatocellular carcinoma (HCC) in Chinese patients and whether there were particular HBx mutations. METHODS: HBx gene was amplified and direct sequencing was used in genomic DNA samples from 20 HCC and c...

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Hlavní autoři: Liu, Xiao-Hong, Lin, Jing, Zhang, Shu-Hui, Zhang, Shun-Min, Feitelson, Mark A, Gao, Heng-Jun, Zhu, Ming-Hua
Médium: Artigo
Jazyk:Inglês
Vydáno: The WJG Press and Baishideng 2008
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2693680/
https://ncbi.nlm.nih.gov/pubmed/18322946
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3748/wjg.14.1346
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