Sphingosine 1-Phosphate Triggers Apoptotic Signal for B16 Melanoma Cells via ERK and Caspase Activation

The bioactive sphingolipid metabolite sphingosine 1-phosphate (S1P), recently was reported to induce apoptosis of some cancer cells and neurons, although it generally known to exert mitogenic and antiapoptotic effects. In this study, we investigated the effects of S1P on the cell growth, melanogenes...

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Bibliografiske detaljer
Main Authors: Shin, Jeong-Hyun, Choi, Gwang-Seong, Kang, Won-Hyung, Myung, Ki-Bum
Format: Artigo
Sprog:Inglês
Udgivet: The Korean Academy of Medical Sciences 2007
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Original Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2693598/
https://ncbi.nlm.nih.gov/pubmed/17449940
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3346/jkms.2007.22.2.298
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