Sphingosine 1-Phosphate Triggers Apoptotic Signal for B16 Melanoma Cells via ERK and Caspase Activation

The bioactive sphingolipid metabolite sphingosine 1-phosphate (S1P), recently was reported to induce apoptosis of some cancer cells and neurons, although it generally known to exert mitogenic and antiapoptotic effects. In this study, we investigated the effects of S1P on the cell growth, melanogenes...

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Bibliografski detalji
Glavni autori: Shin, Jeong-Hyun, Choi, Gwang-Seong, Kang, Won-Hyung, Myung, Ki-Bum
Format: Artigo
Jezik:Inglês
Izdano: The Korean Academy of Medical Sciences 2007
Teme:
Original Article
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2693598/
https://ncbi.nlm.nih.gov/pubmed/17449940
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3346/jkms.2007.22.2.298
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