A phase II experience with neoadjuvant irinotecan (CPT-11), 5-fluorouracil (5-FU) and leucovorin (LV) for colorectal liver metastases

BACKGROUND: Chemotherapy may improve survival in patients undergoing resection of colorectal liver metastases (CLM). Neoadjuvant chemotherapy may help identify patients with occult extrahepatic disease (averting unnecessary metastasectomy), and it provides in vivo chemosensitivity data. METHODS: A p...

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Autores principales: Bathe, Oliver F, Ernst, Scott, Sutherland, Francis R, Dixon, Elijah, Butts, Charles, Bigam, David, Holland, David, Porter, Geoffrey A, Koppel, Jennifer, Dowden, Scot
Formato: Artigo
Lenguaje:Inglês
Publicado: BioMed Central 2009
Materias:
Research Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC2693527/
https://ncbi.nlm.nih.gov/pubmed/19457245
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2407-9-156
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