A phase II experience with neoadjuvant irinotecan (CPT-11), 5-fluorouracil (5-FU) and leucovorin (LV) for colorectal liver metastases

BACKGROUND: Chemotherapy may improve survival in patients undergoing resection of colorectal liver metastases (CLM). Neoadjuvant chemotherapy may help identify patients with occult extrahepatic disease (averting unnecessary metastasectomy), and it provides in vivo chemosensitivity data. METHODS: A p...

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Bibliographic Details
Main Authors: Bathe, Oliver F, Ernst, Scott, Sutherland, Francis R, Dixon, Elijah, Butts, Charles, Bigam, David, Holland, David, Porter, Geoffrey A, Koppel, Jennifer, Dowden, Scot
Format: Artigo
Language:Inglês
Published: BioMed Central 2009
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Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2693527/
https://ncbi.nlm.nih.gov/pubmed/19457245
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2407-9-156
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