Synergistic effect of human CycT1 and CRM1 on HIV-1 propagation in rat T cells and macrophages

BACKGROUND: In vivo studies of HIV-1 pathogenesis and testing of antiviral strategies have been hampered by the lack of an immunocompetent small animal model that is highly susceptible to HIV-1 infection. Although transgenic rats that express the HIV-1 receptor complex hCD4 and hCCR5 are susceptible...

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Detalhes bibliográficos
Main Authors: Okada, Hiroyuki, Zhang, Xianfeng, Ben Fofana, Ismael, Nagai, Mika, Suzuki, Hajime, Ohashi, Takashi, Shida, Hisatoshi
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2009
Assuntos:
Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2693497/
https://ncbi.nlm.nih.gov/pubmed/19435492
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1742-4690-6-43
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