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The cytoskeletal scaffold Shank3 is recruited to pathogen-induced actin rearrangements

The common gastrointestinal pathogens enteropathogenic Escherichia coli (EPEC) and Salmonella Typhimurium both reorganize the gut epithelial cell actin cytoskeleton to mediate pathogenesis, utilizing mimicry of the host signaling apparatus. The PDZ domain-containing protein Shank3, is a large cytosk...

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Autores principales: Huett, Alan, Leong, John M, Podolsky, Daniel K., Xavier, Ramnik J.
Formato: Artigo
Lenguaje:Inglês
Publicado: 2009
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC2693461/
https://ncbi.nlm.nih.gov/pubmed/19371741
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.yexcr.2009.04.003
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