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Structure of the nucleocapsid-binding domain from the mumps virus polymerase; An example of protein folding induced by crystallization

The human pathogen mumps virus, like all paramyxoviruses, encodes a polymerase responsible for virally directed RNA synthesis. The template for the polymerase is the nucleocapsid, a filamentous protein-RNA complex harbouring the viral genome. Interaction of the polymerase and the nucleocapsid is med...

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Detalhes bibliográficos
Main Authors: Kingston, Richard L., Gay, Leslie S., Baase, Walter S., Matthews, Brian W.
Formato: Artigo
Idioma:Inglês
Publicado em: 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2693374/
https://ncbi.nlm.nih.gov/pubmed/18468621
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jmb.2007.12.080
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