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Ibuprofen and other widely used non-steroidal anti-inflammatory drugs inhibit antibody production in human cells

The widely used non-steroidal anti-inflammatory drugs (NSAIDs) function mainly through inhibition of cyclooxygenases 1 and 2 (Cox-1 and Cox-2). Unlike Cox-1, Cox-2 is considered an inducible and pro-inflammatory enzyme. We previously reported that Cox-2 is upregulated in activated human B lymphocyte...

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Detalhes bibliográficos
Main Authors: Bancos, Simona, Bernard, Matthew P., Topham, David J., Phipps, Richard P.
Formato: Artigo
Idioma:Inglês
Publicado em: 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2693360/
https://ncbi.nlm.nih.gov/pubmed/19345936
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cellimm.2009.03.007
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