Genome-wide Linkage of Cotinine Pharmacokinetics Suggests Candidate Regions on Chromosomes 9 and 11

Characterizing cotinine pharmacokinetics is a useful way to study nicotine metabolism because the same liver enzyme is primarily responsible for the metabolism of both, and the clearances of nicotine and cotinine are highly correlated. We conducted a whole-genome linkage analysis to search for candi...

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Main Authors: He, Yungang, Bergen, Andrew W., Hops, Hyman, Andrews, Judy A., Tildesley, Elizabeth, Lessov-Schlaggar, Christina N., Webster, Cris, Benowitz, Neal, Swan, Gary E.
Format: Artigo
Sprog:Inglês
Udgivet: 2009
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2693302/
https://ncbi.nlm.nih.gov/pubmed/18785207
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/ajmg.b.30859
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