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DNA-lesion mapping in mammalian cells
Formation of DNA damage is a crucial event in carcinogenesis. Irreparable DNA lesions have the potential to cause mispairing during DNA replication, thereby giving rise to mutations. Critically important mutations in cancer-related genes, i.e., oncogenes and tumor suppressor genes, are key contribut...
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主要な著者: | , |
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フォーマット: | Artigo |
言語: | Inglês |
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2009
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主題: | |
オンライン・アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2693248/ https://ncbi.nlm.nih.gov/pubmed/19245834 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ymeth.2009.02.008 |
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