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Emergence of patterned stem cell differentiation within multicellular structures

The ability of stem cells to differentiate into specified lineages in the appropriate locations is vital to morphogenesis and adult tissue regeneration. While soluble signals are important regulators of patterned differentiation, here we show that gradients of mechanical forces can also drive patter...

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Bibliografiske detaljer
Main Authors: Ruiz, Sami Alom, Chen, Christopher S.
Format: Artigo
Sprog:Inglês
Udgivet: 2008
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2693100/
https://ncbi.nlm.nih.gov/pubmed/18703661
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1634/stemcells.2008-0432
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