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Automated screening for mutants affecting dopaminergic neuron specification in C. elegans
We describe an automated method to isolate mutant C. elegans animals, which fail to appropriately execute a cellular differentiation program that we monitor with gfp-based reporter gene technology. A fluorescence activated sorting mechanism implemented in the COPAS Biosort machine is able to isolate...
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2008
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2693092/ https://ncbi.nlm.nih.gov/pubmed/18758453 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nmeth.1250 |
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