Depolarization and cAMP Elevation Rapidly Recruit TrkB to the Plasma Membrane of CNS Neurons

Here, we describe a novel mechanism for the rapid regulation of surface levels of the neurotrophin receptor TrkB. Unlike nodose ganglion neurons, both retinal ganglion cells (RGCs) and spinal motor neurons (SMNs) in culture display only low levels of surface TrkB, though high levels are present intr...

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Bibliographic Details
Main Authors: Meyer-Franke, Anke, Wilkinson, George A., Kruttgen, Alex, Hu, Minjie, Munro, Elizabeth, Hanson, Martin G., Reichardt, Louis F., Barres, Ben A.
Format: Artigo
Language:Inglês
Published: 1998
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2693071/
https://ncbi.nlm.nih.gov/pubmed/9808456
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