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The Functionally Exchangeable L Domains in RSV and HIV-1 Gag Direct Particle Release Through Pathways Linked by Tsg101

The functionally exchangeable L domains of HIV-1 and Rous sarcoma virus (RSV) Gag bind Tsg101 and Nedd4, respectively. Tsg101 and Nedd4 function in endocytic trafficking, and studies show that expression of Tsg101 or Nedd4 fragments interfere with release of HIV-1 or RSV Gag, respectively, as virus-...

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Autors principals: Medina, Gisselle, Zhang, Yongjun, Tang, Yi, Gottwein, Eva, Vana, Marcy L., Bouamr, Fadila, Leis, Jonathan, Carter, Carol A.
Format: Artigo
Idioma:Inglês
Publicat: 2005
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2692930/
https://ncbi.nlm.nih.gov/pubmed/16138902
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1600-0854.2005.00323.x
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