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BDNF Activates CaMKIV and PKA in Parallel to Block MAGmediated Inhibition of Neurite Outgrowth

The environment of the adult CNS prevents axonal regeneration after injury. This inhibition of axonal regeneration can be blocked by elevating cAMP. Previously, we showed that the cAMP pathway can be activated via pre-treatment with neurotrophins and requires activation of several signaling pathways...

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Hlavní autoři: Spencer, Timothy K., Mellado, Wilfredo, Filbin, Marie T.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2008
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2692908/
https://ncbi.nlm.nih.gov/pubmed/18381242
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.mcn.2008.02.005
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