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Bicarbonate Contributes to GABA(A) Receptor-Mediated Neuronal Excitation in Surgically-Resected Human Hypothalamic Hamartomas
The role of bicarbonate (HCO(3)(-)) in GABA(A) receptor-mediated depolarization of human hypothalamic hamartoma (HH) neurons was investigated using cellular electrophysiological and calcium imaging techniques. Activation of GABA(A) receptors with muscimol (30 μM) provoked neuronal excitation in over...
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| Main Authors: | , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2008
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2692870/ https://ncbi.nlm.nih.gov/pubmed/19022626 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.eplepsyres.2008.09.008 |
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