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INTRA-HIPPOCAMPAL ADMINISTRATION OF THE VEGF RECEPTOR BLOCKER PTK787/ZK222584 IMPAIRS LONG-TERM MEMORY
A number of studies have established a role for vascular endothelial growth factor (VEGF) in angiogenesis. Recent reports have shown that VEGF overexpression in the hippocampus improves learning and memory and is associated with enhanced neurogenesis. PTK787/ZK222584 (PTK/ZK) is a reported inhibitor...
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| Hauptverfasser: | , , , |
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
2008
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2692845/ https://ncbi.nlm.nih.gov/pubmed/19100245 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.brainres.2008.11.086 |
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