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INTRA-HIPPOCAMPAL ADMINISTRATION OF THE VEGF RECEPTOR BLOCKER PTK787/ZK222584 IMPAIRS LONG-TERM MEMORY

A number of studies have established a role for vascular endothelial growth factor (VEGF) in angiogenesis. Recent reports have shown that VEGF overexpression in the hippocampus improves learning and memory and is associated with enhanced neurogenesis. PTK787/ZK222584 (PTK/ZK) is a reported inhibitor...

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Detalhes bibliográficos
Main Authors: Pati, Shibani, Orsi, Sara A., Moore, Anthony N., Dash, Pramod K.
Formato: Artigo
Idioma:Inglês
Publicado em: 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2692845/
https://ncbi.nlm.nih.gov/pubmed/19100245
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.brainres.2008.11.086
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