Dichotomous Metabolism of Enterococcus faecalis Induced by Hematin Starvation Modulates Colonic Gene Expression

Enterococcus faecalis is an intestinal commensal that cannot synthesize porphyrins and only expresses a functional respiratory chain when provided exogenous hematin. In the absence of hematin, E. faecalis reverts to fermentative metabolism and produces extracellular superoxide that can damage epithe...

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Main Authors: Allen, Toby D., Moore, Danny R., Wang, Xingmin, Casu, Viviana, May, Randal, Lerner, Megan R., Houchen, Courtney, Brackett, Daniel J., Huycke, Mark M.
Format: Artigo
Sprog:Inglês
Udgivet: 2008
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2692828/
https://ncbi.nlm.nih.gov/pubmed/18809545
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1099/jmm.0.47798-0
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