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Dynamin 2 Regulates Granule Exocytosis During NK Cell-Mediated Cytotoxicity

Natural killer (NK) cells are innate immune cells that can eliminate their targets through granule release. Here we describe a specialized role for the large GTPase Dynamin 2 (Dyn2) in the regulation of these secretory events leading to cell-mediated cytotoxicity. By modulating the expression of Dyn...

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Detalhes bibliográficos
Main Authors: Arneson, Laura N., Segovis, Colin M., Gomez, Timothy S., Schoon, Renee A., Dick, Christopher J., Lou, Zhenkun, Billadeau, Daniel D., Leibson, Paul J.
Formato: Artigo
Idioma:Inglês
Publicado em: 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2692694/
https://ncbi.nlm.nih.gov/pubmed/18981119
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