Effect of 6-mo. calorie restriction on biomarkers of longevity, metabolic adaptation and oxidative stress in overweight subjects

CONTEXT: Prolonged calorie restriction (CR) increases lifespan in rodents. Whether prolonged CR affects biomarkers of longevity, markers of oxidative stress, and reduces metabolic rate, beyond that expected from reduced metabolic mass, has not previously been tested in humans. OBJECTIVES: To examine...

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Autori principali: Heilbronn, Leonie K, de Jonge, Lilian, Frisard, Madlyn I, DeLany, James P., Meyer, D. Enette Larson, Rood, Jennifer, Nguyen, Tuong, Martin, Corby K, Volaufova, Julia, Most, Marlene M, Greenway, Frank L, Smith, Steven R, Williamson, Donald A, Deutsch, Walter A, Ravussin, Eric
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2006
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2692623/
https://ncbi.nlm.nih.gov/pubmed/16595757
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1001/jama.295.13.1539
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