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Suppression of RelB-mediated manganese superoxide dismutase expression reveals a primary mechanism for radiosensitization effect of 1α,25-dihydroxyvitamin D(3) in prostate cancer cells

Nuclear factor-κB provides an adaptive response to protect cancer cells against cytotoxicity induced by redox active therapeutics. RelB is uniquely expressed at a high level in prostate cancer with high Gleason scores. Recently, we showed that the level of RelB rapidly increases in androgen-independ...

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Detalhes bibliográficos
Main Authors: Xu, Yong, Fang, Fang, St. Clair, Daret K., Josson, Sajni, Sompol, Pradoldej, Spasojevic, Ivan, St. Clair, William H.
Formato: Artigo
Idioma:Inglês
Publicado em: 2007
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2692592/
https://ncbi.nlm.nih.gov/pubmed/17604335
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1535-7163.MCT-06-0700
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