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Collecting duct-specific Rh C glycoprotein deletion alters basal and acidosis-stimulated renal ammonia excretion

NH(3) movement across plasma membranes has traditionally been ascribed to passive, lipid-phase diffusion. However, ammonia-specific transporters, Mep/Amt proteins, are present in primitive organisms and mammals express orthologs of Mep/Amt proteins, the Rh glycoproteins. These findings suggest that...

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Hlavní autoři: Lee, Hyun-Wook, Verlander, Jill W., Bishop, Jesse M., Igarashi, Peter, Handlogten, Mary E., Weiner, I. David
Médium: Artigo
Jazyk:Inglês
Vydáno: American Physiological Society 2009
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2692449/
https://ncbi.nlm.nih.gov/pubmed/19321595
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajprenal.90667.2008
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