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Ischemic insult to cerebellar Purkinje cells causes diminished GABA(A) receptor function and Allopregnanolone neuroprotection is associated with GABA(A) receptor stabilization
Cerebellar Purkinje cells are particularly vulnerable to ischemic injury and excitotoxicity, although the molecular basis of this sensitivity remains unclear. We tested the hypothesis that ischemia causes rapid down-regulation of GABA(A) receptors in cerebellar Purkinje cells, thereby increasing sus...
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| Main Authors: | , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2008
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2692389/ https://ncbi.nlm.nih.gov/pubmed/18699862 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1471-4159.2008.05617.x |
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