ACTIVATION OF APOPTOSIS BY 1-HYDROXY-5, 7-DIMETHOXY-2-NAPHTHALENE-CARBOXALDEHYDE (HDNC), A NOVEL COMPOUND FROM AEGLE MARMELOS

We have identified a natural compound that activates apoptosis of epithelial cancer cells through activation of TNF-α, TRADD and caspases. The molecule, 1-hydroxy-5, 7-dimethoxy-2-naphthalene-carboxaldehyde (HDNC, marmelin) was isolated and characterized from ethyl acetate fraction of extracts of Ae...

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Main Authors: Subramaniam, Dharmalingam, Giridharan, Periyasamy, Murmu, Nabendu, Shankarnarayanan, N.P., May, Randal, Houchen, Courtney W., Ramanujam, Rama P., Balakrishnan, Arun, Vishwakarma, Ram A., Anant, Shrikant
Formato: Artigo
Idioma:Inglês
Publicado em: 2008
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2692325/
https://ncbi.nlm.nih.gov/pubmed/18922933
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/0008-5472.CAN-08-2372
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