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Differences between high- and low-affinity complexes of enzymes and non-enzymes
Physical differences in small molecule binding between enzymes and non-enzymes were found through mining the protein-ligand database, Binding MOAD (Mother of All Databases). The data suggest that divergent approaches may be more productive for improving the affinity of ligands for the two classes of...
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| Main Authors: | , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2008
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2692211/ https://ncbi.nlm.nih.gov/pubmed/18826206 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/jm8006504 |
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