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Hippocampal Place Cell Firing Patterns Can Induce Long-Term Synaptic Plasticity In Vitro

In the hippocampus, synaptic strength between pyramidal cells is modifiable by NMDA receptor (NMDAR)-dependent long-term potentiation (LTP) and long-term depression (LTD), both of which require coincident presynaptic and postsynaptic activity. In vivo, many pyramidal cells exhibit location-specific...

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Detalhes bibliográficos
Main Authors: Isaac, John T. R., Buchanan, Katherine A., Muller, Robert U., Mellor, Jack R.
Formato: Artigo
Idioma:Inglês
Publicado em: Society for Neuroscience 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2692101/
https://ncbi.nlm.nih.gov/pubmed/19474311
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.0731-09.2009
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