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Development and validation of a solid-phase extraction gas chromatography–mass spectrometry method for the simultaneous quantification of methadone, heroin, cocaine and metabolites in sweat

A sensitive and specific method is presented to simultaneously quantify methadone, heroin, cocaine and metabolites in sweat. Drugs were eluted from sweat patches with sodium acetate buffer, followed by SPE and quantification by GC/MS with electron impact ionization and selected ion monitoring. Daily...

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Библиографические подробности
Главные авторы: Brunet, Bertrand R., Barnes, Allan J., Scheidweiler, Karl B., Mura, Patrick, Huestis, Marilyn A.
Формат: Artigo
Язык:Inglês
Опубликовано: 2008
Предметы:
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC2692071/
https://ncbi.nlm.nih.gov/pubmed/18607576
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00216-008-2228-0
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