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Drosophila Pico and Its Mammalian Ortholog Lamellipodin Activate Serum Response Factor and Promote Cell Proliferation

MIG-10/RIAM/lamellipodin (MRL) proteins link activated Ras-GTPases with actin regulatory Ena/VASP proteins to induce local changes in cytoskeletal dynamics and cell motility. MRL proteins alter monomeric (G):filamentous (F) actin ratios, but the impact of these changes had not been fully appreciated...

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Detalhes bibliográficos
Main Authors: Lyulcheva, Ekaterina, Taylor, Eleanor, Michael, Magdalene, Vehlow, Anne, Tan, Shengjiang, Fletcher, Adam, Krause, Matthias, Bennett, Daimark
Formato: Artigo
Idioma:Inglês
Publicado em: Cell Press 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2691947/
https://ncbi.nlm.nih.gov/pubmed/19000833
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.devcel.2008.09.020
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