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Identification of C-glycoside analogues that display a potent biological activity against murine and human invariant natural killer T cells

We have recently shown that α-C-galactosylceramide (α-C-GalCer) stimulates invariant natural killer T (iNKT) cells and preferentially induces a T helper 1 (Th1)-type response in mice. However, α-C-GalCer was found to be a rather weak ligand against human iNKT cells in vitro. Therefore, in this study...

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Hlavní autoři: Li, Xiangming, Chen, Guangwu, Garcia-Navarro, Raquel, Franck, Richard W, Tsuji, Moriya
Médium: Artigo
Jazyk:Inglês
Vydáno: Blackwell Science Inc 2009
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2691787/
https://ncbi.nlm.nih.gov/pubmed/19489127
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1365-2567.2008.02943.x
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