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TLR2 synergizes with both TLR4 and TLR9 for induction of the MyD88-dependent splenic cytokine and chemokine response to Streptococcus pneumoniae

We previously demonstrated that induction of splenic cytokine and chemokine secretion in response to Streptococcus pneumoniae (Pn) is MyD88-, but not critically TLR2-dependent, suggesting a role for additional TLRs. In this study, we investigated the role of TLR2, TLR4 and/or TLR9 in mediating this...

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Détails bibliographiques
Auteurs principaux: Lee, Katherine S., Scanga, Charles A., Bachelder, Eric M., Chen, Quanyi, Snapper, Clifford M.
Format: Artigo
Langue:Inglês
Publié: 2007
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC2691573/
https://ncbi.nlm.nih.gov/pubmed/17521621
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cellimm.2007.04.003
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