Relationship between oxidative stress and hepatic glutathione levels in ethanol-mediated apoptosis of polarized hepatic cells

AIM: To investigate the role of reactive oxygen species (ROS) in ethanol-mediated cell death of polarized hepatic (WIF-B) cells. METHODS: In this work, WIF-B cultures were treated with pyrazole (inducer of cytochrome P4502E1, CYP2E1) and/or L-buthionine sulfoximine (BSO), a known inhibitor of hepati...

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Hlavní autoři: McVicker, Benita L, Tuma, Pamela L, Kharbanda, Kusum K, Lee, Serene ML, Tuma, Dean J
Médium: Artigo
Jazyk:Inglês
Vydáno: The WJG Press and Baishideng 2009
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2691491/
https://ncbi.nlm.nih.gov/pubmed/19496190
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3748/wjg.15.2609
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