Cargando...

Prediction of Modified Release Pharmacokinetics and Pharmacodynamics from In Vitro, Immediate Release, and Intravenous Data

The aim of this study was to demonstrate the value of mechanistic simulations in gaining insight into the behaviors of modified release (MR) formulations in vivo and to use the properly calibrated models for prediction of pharmacokinetics (PK) and pharmacodynamics (PD). GastroPlus(TM) (Simulations P...

Descrición completa

Gardado en:
Detalles Bibliográficos
Main Authors: Lukacova, Viera, Woltosz, Walter S., Bolger, Michael B.
Formato: Artigo
Idioma:Inglês
Publicado: Springer US 2009
Assuntos:
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC2691467/
https://ncbi.nlm.nih.gov/pubmed/19430911
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1208/s12248-009-9107-2
Tags: Engadir etiqueta
Sen Etiquetas, Sexa o primeiro en etiquetar este rexistro!